Commander Shepard and literally anyone
Easily the most notorious pairings in videogame history have been between Commander Shepard and associates throughout the Mass Effect series (2007––). Players may create a male or female avatar for their interplanetary sci-fi adventures, after which they may pursue romantic interest with the same or opposite sex, also between beings from other worlds.
Haytham Kenway and Kaniehtí:io
With Assassin’s Creed III (2012), Ubisoft moved away from the swashbuckling escapades of fan-favorite Ezio Auditore da Firenze and presented a more sombre depiction of Assassin history. The seafaring Templar Haytham Kenway attempts to manipulate a native American warrior and negotiator named Kaniehtí:io. Their fated pairing conceives a conflicted child.